What will we do when there are a billion genomes?

We develop computational approaches to make sense of genetic variation.
And we learn to design biological tools for environmental and human health.

Marks Lab Github
SARS-CoV-2
EVcouplings Server


Research Topics

Disorder, Gels, and Biostasis

Antibiotic Resistance

Protein Design

Structural Information from Evolutionary Interactions

Neurodegenerative Diseases

Antibody Design


Featured Publications

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